Search results for "Oral fluid"

showing 3 items of 3 documents

Passive exposure to nicotine from e-cigarettes

2016

A procedure based on the use of ion mobility spectrometry (IMS), after liquid-liquid microextraction (LLME), has been successfully employed for the determination of passive exposure to nicotine from cigarette and e-cigarette smoking. Nicotine has been determined in exhaled breath and oral fluids of both, active and passive smokers. The aforementioned studies, made in closed environments, evidenced that the exhaled breath after conventional blend cigarette smoke provides nicotine levels of the order of 220 ng per puff, in the case of experienced smokers, being exhaled only 32 ng in the case of e-cigarettes. On the other hand, the nicotine amount in oral fluids of passive vapers was between 8…

Bodily SecretionsNicotineLiquid Phase MicroextractionElectronic Nicotine Delivery Systems01 natural sciencesAnalytical ChemistryNicotine03 medical and health sciences0302 clinical medicinemedicineHumansCigarette smoke030212 general & internal medicineChromatographyChemistry010401 analytical chemistryEnvironmental ExposurePassive ExposureEnvironmental exposureExhaled air0104 chemical sciencesBreath TestsOral fluidTobacco Smoke PollutionBodily secretionsmedicine.drugTalanta
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Determination of Third-Generation Synthetic Cannabinoids in Oral Fluids.

2020

Abstract A procedure has been developed for the determination of third-generation synthetic cannabinoids in oral fluid samples by using a semi-automated microextraction by packed sorbent (MEPS) procedure and gas chromatography–mass spectrometry (GC–MS) determination. Five synthetic cannabinoids were employed as model compounds 5F-ADB, MMB-CHMICA, THJ-2201, CUMYL-4CN-BINACA and MDMB-CHMCZCA. The most adequate operative conditions for MEPS were evaluated giving quantitative recoveries, from 89 to 124%, in synthetic and field saliva samples spiked with 125 and 250 μg/L of the studied cannabinoids, with the exception of MDMB-CHMCZCA in field saliva samples that provided slightly lower recoverie…

SalivaSorbentHealth Toxicology and MutagenesisToxicologyMass spectrometry01 natural sciencesGas Chromatography-Mass SpectrometryAnalytical Chemistry03 medical and health sciences0302 clinical medicineSynthetic cannabinoidsmedicineEnvironmental Chemistry030216 legal & forensic medicineSalivaDetection limitChemical Health and SafetyChromatographyChemistryCannabinoidsIllicit Drugs010401 analytical chemistryThird generation0104 chemical sciencesOral fluidGas chromatography–mass spectrometrymedicine.drugJournal of analytical toxicology
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Molecularly imprinted polymer-based device for field collection of oral fluid samples for cocaine identification.

2020

In this paper, a low-cost, rapid, easy, and potentially portable tool for the identification of cocaine and its semi-quantitative determination in oral fluid has been proposed. A field collection device has been designed, based on a cotton pad with an indicator and a molecularly imprinted polymer (MIP) sorbent, to selective retain cocaine from oral fluid components. After sample collection, cocaine is transferred by using phosphate buffer to the MIP and then eluted with 2-propanol. The obtained extract is analysed by ion mobility spectrometry (IMS), providing a cut-off value of 20 µg L-1 that identifies 100 % true-positive and 95 % true-negative samples. The MIP-IMS procedure has been valid…

ChromatographyElutionIon-mobility spectrometryChemistryPolymers010401 analytical chemistryOrganic ChemistryMolecularly imprinted polymerGeneral Medicine010402 general chemistry01 natural sciencesBiochemistry0104 chemical sciencesAnalytical ChemistryMolecular ImprintingSubstance Abuse DetectionHealth personnelIdentification (information)CocaineIon Mobility SpectrometryOral fluidHumansSample collectionSalivaLateral flow immunoassayJournal of chromatography. A
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